The following positions are currently available in the Parkinson Lab:
The Parkinson lab is currently seeking a talented and motivated bioinfromatician to explore the organization and operation of Bacterial interactomes. Previously, in collaboration with Andrew Emili and Jack Greenblatt at the University of Toronto, we have generated global interaction maps of the cytoplasmic interactome that captures the vast majority of soluble proteins in E. coli (see our Bacteriome web resource). These maps are beginning to provide unprecedented insights into the organization of protein complexes participating in core processes such as translation, transcription and metabolism. With the integration of additional datasets, we are now starting to explore how these complexes have evolved and operate in the context of biochemical pathways. Funded for a further five years by the Canadian Institute for Health Research, we are expanding these efforts to include the ~1,000 putative membrane proteins of E. coli. The current position is ideal for a bioinformatician with interests in the systems biology of bacteria. Proposed duties include:
The individual will join an established team of computational biologists with interests in exploring the organization and evolution of biological systems in the context of human disease. The Parkinson lab is situated within the Hospital for Sick Children, recognized as one of the world's foremost paediatric academic health-care institutions. Affiliated with the University of Toronto and with an annual research budget of almost $150 million, the research institute at SickKids is one of the largest in Canada, employing over 1200 research staff pioneering many aspects of both basic and clinical science. Our lab is located on the top floor of the MaRS Discovery Tower in close proximity to the University of Toronto (to which we are affiliated) and the other major research hospitals in Toronto.Qualifications:
The ideal candidate will have a PhD in Bioinformatics or Computational Biology with a strong background in statistics together with a solid knowledge of microbiology. The applicant should be familiar with Perl and Java and have experience with relational databases such as PostgreSQL. Strong verbal and written skills and the ability to work effectively within a Team environment are also essential. We are particularly interested in self-motivated individuals who are interested in providing their own creativity and scope to the project.
The position is available for three years in the first instance with further possibilities of extension available. To apply please send resume and contact details to John Parkinson - email@example.com
Prospective graduate students who are considering joining the Parkinson lab need to first be accepted into the graduate program in either the Department of Biochemistry or Molecular Genetics at the University of Toronto. Candidates should be aware that the research undertaken in the Parkinson lab is predominantly computationally based. Although we have limited access to wet lab space, students will be expected to have a strong interest in applying computational approaches to understanding biological problems. While experience of programming (particularly in Perl, C or Java) and/or training in Bioinformatics or related discipline would be advantageous, we would be happy to consider those coming from a more biologically oriented background.
A guide providing some useful tips for graduate students exists on our local wiki (currently unavailable).
Our lab tends to hire 1-2 Co-op students per work term. If you are interested in joining the group please contact us at least several months in advance so that we can initiate the process.return to Understanding Biological Complexity