Protein interactions
Three interaction datasets are presented: a 'core' set of high quality protein-protein interactions (PPI) derived from an ongoing series of TAP-TAG pulldown experiments; an 'Extended' set of interactions which includes the core set, but also includes an additional set of PPI's deemed to be of slightly lower uqality to the core set; and a set of predicted functional linkages, derived through a theoretical integration of various functional genomic datasets. See the help pages for more details on the construction of the various datasets.
| Total number of proteins | Number of identified interactions | Average number of interactions per protein | |
|---|---|---|---|
| core - experimental | 918 | 3888 | 4.24 |
| extended - experimental | 2291 | 7220 | 2.49 |
| functional - theoretical | 1941 | 3989 | 2.06 |
The Bacteriome resource provides access to two sets of protein complex predictions - one for the functional interaction dataset and one for the core dataset. Note for the functional interaction dataset, the complexes may be thought of as 'functional modules'.
| Number of protein complexes | Total number of proteins | Maximum complex size | Minimum complex size | Medium complex size | Average complex size | |
|---|---|---|---|---|---|---|
| core - experimental | 68 | 967 | 98 | 3 | 6 | 14.22 |
| functional - theoretical | 279 | 1370 | 30 | 3 | 4 | 4.91 |
In addition to the interactions and complexes, the Bacteriome resource integrates a variety of additional "Metadata" which is used to provide additional detail on selected genes and aid in the visualization of the networks. Some examples of these datasets are provided below:
|
Total number of proteins/genes in database: Total number of journals referenced: Total number of distinct protein domains: Total number of genomes used to build phyloegenetic profiles: |
4510 9344 1889 199 |
|---|
